News & Stories

The new AI-based model uses genetic information to predict an individual’s risk of developing AD well before symptoms occur.

To discover and thoroughly demonstrate the newly identified noncanonical cleavage mechanism, the Hong Kong University of Science and Technology (HKUST) research team, led by Prof. Tuan Anh Nguyen, Assistant Professor of the Division of Life Science, used several sophisticated techniques, such as miRNA sequencing, pri-miRNA structure analysis, and high-throughput pri-miRNA cleavage assays for approximately 260,000 pri-miRNA sequences. In contrast to the canonical mechanism, the noncanonical mechanism does not rely on several essential protein and RNA elements required for the canonical mechanism. The study also revealed previously unrecognized DROSHA recognition sites (DRES), which are critical for noncanonical cleavage but can also function in the canonical cleavage mechanism.

A team of HKUST researchers has developed a method to customize materials to treat three chronic conditions and potentially many others.

Ice surfaces have a thin layer of water below its melting temperature of 0℃. Such premelting phenomenon is important for skating and snowflake growth. Similarly, liquid often crystallizes into a thin layer of crystal on a flat substrate before reaching its freezing temperature, i.e. prefreezing. The thickness of the surface layer usually increases and diverges as approaching the phase transition (such as melting and freezing) temperature. Besides premelting and prefreezing, whether similar surface phenomenon exists as a precursor of a phase transition has rarely been explored.

A research team from the Hong Kong University of Science and Technology (HKUST) has developed the world’s most productive chemical synthesis which could yield antibiotic anthracimycin and anthracimycin B that is 63 times more than current method.  The breakthrough greatly advances the development of anthracimycin-based antibiotics to combat the deadly bacteria infections caused by antibiotic-resistant bacteria and even superbugs.

    Researchers at the Hong Kong University of Science and Technology (HKUST) have found that children think more highly of the naturally talented over hard workers, a preference that they carry into adulthood.     That is the case even in China, a culture that places effort above natural talent as people perceive the naturally talented as being more competent than those who work hard, according to the study.     Although children’s preference for naturals also generalizes to the perception of their friendliness and a willingness to interact with them, Chinese adults do not prefer naturals over hard workers except when considering competence, the study found.

Researchers at the Hong Kong University of Science and Technology (HKUST) developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method. This breakthrough facilitates cancer research for some of the most complex and rare tumors, opening new directions for drug target discovery in the future.

    The study of microRNAs (miRNAs), small RNAs that play important roles in gene regulation in animals and humans alike, have long been a topic of interest to many. How these miRNAs control and regulate gene expression, a subject of great importance in biology and medicine, is often believed to hold the keys to providing effective cures, or strategies, to different phenomenon and symptoms, such as cancer, a result of cell mutations.